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Ultrasound Course Module 5
Biometry, Prenatal Diagnosis, and Doppler

Lesson 2: Biometry — Multiple Measurements (BPD/HC/AC/FL)

  1. Estimation of Fetal Weight
    • Hadlock Nomogram: HC, AC, FL
    • Shepard Nomogram: AC, FL
    • 3 weeks minimum interval for growth studies
    • Indirect measure of the variable of interest
    • Fair predictor (+/- 10-15 %) in normal fetuses
    • Poor predictor in LGA, SGA, or asymmetric fetuses
  2. Small Babies
    1. SGA (EFW < 5th percentile for ega)
    2. Etiology:
      1. 40-50% small but normal (no pathology)
      2. 30-40% uteroplacental etiology
      3. 10-20% maternal factors
      4. 5-10% fetal abnormality
  3. Growth — Restricted vs. Small-But-Normal
    1. HC/AC ratio:
    2. Highly predictive of IUGR in at-risk populations.
    3. Poorly predictive in normal populations.
    4. Reflects "head-sparing" effect.
    5. FL:AC — may reflect IUGR if abnormal.
      • If low, may reflect IUGR (Hadlock FP, Deter RL, Harrist RB, Roecker E, Park SK. A date-independent predictor of intrauterine growth retardation: Femur length/abdominal circumference ratio. AJR Am J Roentgenol 1983;141(5):979-84)
    6. Oligohydramnios.

      Normal umbilical artery systolic
      to diastolic ratio (S/D)



      Normal MCA of 52.9 cm seconds at
      32 weeks in a Duffy sensitized patient
    7. Predisposing maternal conditions.
    8. Doppler velocimetry:
      • Umbilical artery
      • Cerebral artery
  4. Large Babies
    1. U/S EFW is very unreliable for large fetuses.
    2. U/S EFW is a poor predictor of:
      • Abnormal labor progress
      • Shoulder dystocia
      • Actual birth weight (10-20% error rate)
    3. FL:AC — may reflect IUGR if abnormal.
      • if high. may reflect macrosomia (Hadlock FP, Deter RL, Harrist RB, Roecker E, Park SK. A date-independent predictor of intrauterine growth retardation: Femur length/abdominal circumference ratio. AJR Am J Roentgenol 1983;141(5):979-84)
    4. Consider:
      • Repeating glucose challenge (esp. w/increased fluid)
      • Early Induction for macrosomia is questionable